HIBM (Hereditary Inclusion Body Myopathies) are a group of genetic disorders , which are uncommon in the general world population. HIBM causes progressive muscle wasting and weakness that can lead to severe disability. The autosomal recessive form([[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600737|IBM2]] or [[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=605820|DMRV]]) is more common in people with a Middle Eastern, Jewish or Japanese heritage, but patients can be found in every community. HIBM has been identified in other minorities throughout the world. Patients of Asian (Japanese, Korean, Chinese and others), European, and South American origin, as well as Muslim patients in the Middle Eastern, Palestinian, and Iranian origin, have been identified. In Japan and many East Asian countries, this disorder is known as Distal Myopathy with Rimmed Vacuoles (DMRV). | HIBM (Hereditary Inclusion Body Myopathies) are a group of genetic disorders , which are uncommon in the general world population. HIBM causes progressive muscle wasting and weakness that can lead to severe disability. The autosomal recessive form GNE Myopathy, ([[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600737|IBM2]] or [[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=605820|DMRV Nonaka Myopathy]]) is more common in people with a Middle Eastern, Jewish or Japanese heritage, but patients can be found in every community. HIBM has been identified in other minorities throughout the world. Patients of Asian (Japanese, Korean, Chinese and others), European, and South American origin, as well as Muslim patients in the Middle Eastern, Palestinian, and Iranian origin, have been identified. In Japan and many East Asian countries, this disorder is known as Distal Myopathy with Rimmed Vacuoles (DMRV). |